自1991年以來，超音波導引子宮內膜穿刺手術已被當成避免外科手術的替代治療方案。藉由囊腫穿刺能減小腫瘤體積，破壞囊腫壁，減輕沾黏情形與提升復原機會；但如祇執行單純囊腫穿刺手術而未施行其他附加治療的易引發高復發率(28.5%至100%)。所以為了降低因穿刺手術造成的高復發率，一些醫療團體已採用結合超音波導引子宮內膜穿刺手術合併四環素、甲氨蝶呤，或白細胞介素-2灌流的治療方式，其復發率依次分別為46.9%、18.1%與40%。臨床療效的參考標準，多以對單一子宮內膜囊腫施行乙醇灌流達10分鐘的復發率(14.9%)作為評斷的基準點。
本研究與國內某醫學中心所屬生殖醫學中心合作，針對曾接受過子宮內膜異位相關手術後復發之病患資料做研究，本研究依據診斷定義、臨床症狀與治療措施，規劃匯入臨床病例資料利用資料探勘的技術與分析，以囊腫數量作為決策樹分析預測的項目，發掘出有用的特徵以及彼此相互間的關聯性，試圖將來源資料中隱藏的資訊挖掘出來，運用決策樹將資料依據不同的變數循序產生分析結果，分析資料之特質與異同點，期望能找出與檢驗數據與臨床症狀相關重要決策因子，提供臨床專科醫師診斷與治療的參考。

Ultrasound guided aspiration of ovarian endometrioma had been tried as an alternative therapeutic modality in patients who undesired for surgery or surgical approach is contraindicated since 1991. But simple aspiration leaves the capsule without treatment that results in high recurrence rate (28.5% to 100%).  In order to reduce recurrence after aspiration, some groups have combined ultrasound-guided aspiration with instillation of tetracycline,  methotrexate,  recombinant interleukin-2,  with the recurrence rates of 46.9%, 18.1%, and 40% respectively.  Noma et al. reported that conduct of ethanol instillation for more than 10 minutes particularly for a case with a single endometrial cyst is considered most effective from the standpoint of recurrence (14.9%).
This research works together with Reproduction Medicine Center of Medicine Center in Taiwan Area. Our goal is to analyse patients with recurrent pelvic cyst who underwent surgical intervention. The research data basis clinical diagnosis, symptoms and medical intervention classification, and define the cyst numbers as forecast project target. We try to use decision tree, methodology of data mining technology, to find the useful characteristic as well as each other mutually connection. The expectation can discover with examines the data and the clinical symptom correlation important decision-making factor, provides clinical faculty doctor to diagnose and the treatment reference.

第一章 導論	1
1.1 前言	1
1.2 研究動機	3
1.3 研究目的	6
1.4 論文架構	8
第二章文獻探討	10
2.1 子宮內膜異位症(Endometriosis)	10
2.1.1 解剖構造(Anatomy)	10
2.1.2 病理(Pathology)	11
2.1.3 臨床徵象(Symptoms)	14
2.1.4 診斷(Diagnosis)	15
2.1.5 治療措施(Treatment)	17
2.2 資料探勘(Data Mining)	20
2.3 決策樹(Decision Tree)	23
2.3.1 決策樹演算法原理	25
2.3.2 決策樹分岔準則計算	30
2.3.3 CART決策樹	31
第三章 研究步驟	34
3.1 分析作業流程	35
3.2 分析資料之準備	37
第四章 研究結果	43
4.1 分析目標	44
4.2 決策樹分析結果	45
第五章 結論與未來建議	56
參考文獻	58
附錄-英文論文  62
 
圖目錄
圖2.2 Kdnuggets 2005年2月票選最常使用的資料探勘技術 24
圖2.3 Kdnuggets 2006年4月票選最常使用的資料探勘技術 24
圖2.4 Kdnuggets 2007年3月票選最常使用的資料探勘技術 25
圖2.3.1 電信公司合約到期三個月後拆機率決策樹模型 26
圖3.1 知識探勘流程 34
圖3.2 分析作業流程圖 37
圖3.2.2 囊腫數量部分原始資料部份數據 41
圖4.1.1 囊腫數量資料轉換部份數據 45
圖4.2.1 囊腫數量>=1.5決策樹演算分析結果 45
圖4.2.2 囊腫數量<1.5決策樹演算分析結果 47
圖4.2.3 囊腫數量<1.5個，且CA125檢驗值大於或等於9.7 U/ml，且未合併罹患PID或是CA125 During Bleeding囊腫數量分布圖 48
圖4.2.4 囊腫數量<1.5個， CA125檢驗值大於或等於9.7 U/ml，未合併罹患PID或是CA125 During Bleeding病患術前給藥種類分布圖 49
圖4.2.5 囊腫數量<1.5個，且CA125檢驗值大於或等於9.7 U/ml，且未合併罹患PID或是CA125 During Bleeding病患合併症種類分布圖 50
圖4.2.6 囊腫數量<1.5個，且CA125檢驗值大於或等於9.7 U/ml，且未合併罹患PID或是CA125 During Bleeding病患囊腫穿刺藥物留滯時間分布圖 51
圖4.2.7 囊腫數量<1.5個，且CA125檢驗值大於或等於9.7 U/ml，且未合併罹患PID或是CA125 During Bleeding病患囊腫穿刺藥物種類分布圖 51
圖4.2.8 病患囊腫穿刺治療決策樹分析結果 52
圖4.2.9 病患囊腫數量大於1.5個，且囊腫大小小於6.55公分，接受Alcohol灌流或留置時間案例數 53
圖4.2.10 病患囊腫數量小於1.5個，且接受Alcohol灌流或留置囊腫大小分布圖 54
圖4.2.11 病患囊腫數量小於1.5個，且接受Alcohol灌流或留置時間案例數 54

 
表目錄
表3.2.1 囊腫數量相關欄位 40
表3.2.2 選擇作為決策樹演算分析的欄位一覽表 41

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