淡江大學覺生紀念圖書館 (TKU Library)

系統識別號 U0002-2706201102425000
中文論文名稱 隅角開放型青光眼之眼球流場與壓力分析
英文論文名稱 The Analysis of Fluid Dynamics and Pressure in the Eyes of Open-Angle Glaucoma
校院名稱 淡江大學
系所名稱(中) 機械與機電工程學系碩士班
系所名稱(英) Department of Mechanical and Electro-Mechanical Engineering
學年度 99
學期 2
出版年 100
研究生中文姓名 張又仁
研究生英文姓名 You-Ren Chang
學號 698371233
學位類別 碩士
語文別 中文
口試日期 2011-06-24
論文頁數 55頁
口試委員 指導教授-李宗翰
中文關鍵字 隅角開放型青光眼  眼壓  視神經 
英文關鍵字 Open-Angle Glaucoma  Intraocular pressure  Aqueous Humor 
學科別分類 學科別應用科學機械工程
中文摘要 隅角開放型青光眼是青光眼中最常見的三大類型的其中一種,且經常伴隨著家族遺傳。其發生的原因是由於前房小樑網組織發生了問題,使得眼球前房引流系統異常,導致房水排出時受到阻礙而迫使眼壓升高,壓迫視神經,造成視神經盤凹陷與視野產生缺陷。


英文摘要 Primary Open Angle Glaucoma (POAG) is one of the three most common types of glaucoma, and is often associated with family disease history. The major cause for POAG is the adhesion at anterior trabecular meshwork tissue. This makes drainage system fails to function normally in anterior chamber, causes aqueous from anterior chamber hampered, and increased intraocular pressure. Then, Optic nerve is suppressed, optic disc is damaged, and visual field eventually is reduced.

The numerical model constructed in this study is to simulate the mechanism in forming POAG. Aqueous is generated from posterior chamber and flows into anterior chamber. As drainage system hampered, intraocular pressure increases and acts on the lens which creates oppression on vitreous and passes on the impact to optic nerve.

The results show that the pressure in the eyes of primary open angle glaucoma does transmit from lens to vitreous and actually affect the optic nerve on the back of an eye. This leads to optic nerve compression and vision defects.
論文目次 目錄
第一章 緒論1
1-1 前言1
1-2 研究動機與背景2
1-3 文獻回顧5
第二章 眼球構造、房水與眼壓7
2-1 眼球構造7
2-2 房水10
2-3 眼壓13
第三章 研究方法15
3-1 有限元素法理論15
3-2 數值分析理論16
3-3 收斂檢測21
3-4 應用軟體22
第四章 分析元素、材料參數與邊界條件設定27
4-1 定義分析元素27
4-2 設定材料參數29
4-3 建立實體模型31
4-4 初始條件34
4-5 負載條件36
第五章 結果與討論37
5-1 隅角開放型青光眼37
5-2 前後房房水壓力模擬39
第六章 結論與未來展望46
6-1 結論46
6-2 未來展望48

圖4-2 SOLID45元素圖28


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