青光眼，是僅次於白內障的致盲性眼疾。某些因素造成房水排出受阻時，房水即迫使眼壓升高，進而傷害視神經，導致視力完全喪失。隅角開放型青光眼，是由於小樑網組織出了問題，導致房水流不出去造成眼壓升高的一種青光眼。
     本研究主要在探討隅角開放型青光眼，從房水生成、受阻、對於玻璃體的擠壓，乃至於造成玻璃體外部的壓力分佈狀況，並對於視神經周圍細胞的影響進行探討。

Glaucoma is the second blindness diseases other than cataracts. If the pathway of aqueous humor somehow is forced and blocked up, the intraocular pressure will rise over the bearable limits of optical inner structures that leads to the damage of optic nerve, visual field loss, and ultimately sight loss. The open angle glaucoma is indicated by defect of trabecular meshwork tissue which leads to intraocular pressure hypertension via aqueous obstruction.
In this thesis, a simulation mechanism of angle-closured glaucoma is proposed. The process is associated with increased intraocular pressure resulting from malfunction of aqueous drainage structures and malformation of vitreous body. Hence it damages the surrounding structures including optic nerves.

目錄
中文摘要…………………………………………………………………I
目錄……………………………………………………………………III
圖目錄……………………………………………………………………V
表目錄…………………………………………………………………VII
第一章 序論………………………………………………………………1
1-1 前言…………………………………………………………………1
1-2 研究背景與研究動機………………………………………………4
1-3 文獻回顧……………………………………………………………9
第二章 研究方法………………………………………………………11
2-1 應用軟體…………………………………………………………11
2-2 研究過程…………………………………………………………13
第三章 分析理論………………………………………………………15
3-1 有限元素法理論…………………………………………………15
3-2 流場模型分析理論………………………………………………18
3-3 收斂檢測…………………………………………………………24
第四章 分析元素、材料參數與邊界條件設定………………………25
4-1 選定分析元素……………………………………………………25
4-2 設定材料參數……………………………………………………27
4-3 建立分析模型……………………………………………………29
4-4 初始條件…………………………………………………………31
4-4-1 負載條件………………………………………………………35
第五章 隅角開放型青光眼前後房房水壓力模擬……………………36
5-1隅角開放型青光眼…………………………………………………36
5-2前後房房水壓力模擬………………………………………………37
第六章 結論……………………………………………………………47
第七章 未來展望………………………………………………………49
參考文獻…………………………………………………………………50
專有名詞中英文對照表…………………………………………………54

圖目錄
圖1-1青光眼後期之視野…………………………………………………2
圖1-2眼球構造剖面示意圖………………………………………………5
圖1-3房水流動示意圖……………………………………………………5
圖2-1ANSYS分析處理作業流程圖………………………………………12
圖2-2 研究過程流程圖…………………………………………………14
圖4-1 FLUID142元素圖…………………………………………………25
圖4-2SOLID45元素圖……………………………………………………26
圖4-3 眼球前後房模型…………………………………………………30
圖4-4 眼球前後房模型網格圖…………………………………………30
圖4-5（a）房水流場設定圖……………………………………………32
圖4-5（b）房水流場設定圖……………………………………………33
圖4-6 模擬負載條件示意圖……………………………………………35
圖5-1 隅角開放型青光眼房水流動示意圖……………………………36
圖5-2 前後房水所造成眼壓之壓力分佈………………………………38
圖5-3 前後房水流場圖…………………………………………………38
圖5-4 前後房水流線圖…………………………………………………39
圖5-5 壓力改變後前後房水之壓力分佈………………………………41
圖5-6 壓力改變後前後房水流場圖……………………………………41
圖5-7 壓力改變後前後房水流線圖……………………………………42
圖5-8（a）隅角開放型青光眼眼壓壓力分佈圖………………………44
圖5-8（b）隅角開放型青光眼眼壓壓力分佈圖………………………44
圖5-8（c）隅角開放型青光眼眼壓壓力分佈圖………………………45
圖5-9 前後房流場分布圖………………………………………………45
圖5-10隅角開放型青光眼眼壓壓力分佈圖……………………………46

表目錄
表4-1 房水材料參數表…………………………………………………27
表4-2 水晶體材料參數表………………………………………………28
表4-3 玻璃體材料參數表………………………………………………28

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