本文主要是在探討奈米金在不同金屬鹽類的添加下成長的情況。本實驗主要在探討以金奈米棒以及啞鈴形之金奈米棒作為核心，來合成金銀核殼的奈米粒子；本實驗主要使用兩種保護劑，包含陽離子型的Cetyltrimethylammonium bromide (CTAB)以及陰離子型的Sodium dodecyl sulfate (SDS)做為反應的環境，先在CTAB的條件下，將金奈米棒合成出來以後，藉由系統轉移把金奈米棒置換到SDS的陰離子系統當中，最後再進行包銀。實驗中主要分成金奈米棒(GNRs)以及啞鈴型金奈米棒(AuDBs)去進行包銀，分別在室溫條件進行逐次包銀及高溫條件下的一次性包銀，亦發現若添加金屬鹽類物質(如 NaBr、NaCl)，會對反應時間發生變化；甚至會影響金銀核殼奈米粒子的形狀的比例。藉由改變添加的金屬鹽類、溫度變化、EDTA修飾等處理，進而合成出矩形、雙四角錐、不規則等多樣形態，也對型態控制及均勻度控制做進一步的了解。

In this research we pay attention on the synthesis of Gold Nanorods (GNRs) and Au Dumbbells (AuDBs) as core to format Au-Ag core-shell nanoparticles. At experiment we use two different type of surfactants, Cetyltrimethylammonium bromide (CTAB) and Sodium dodecyl sulfate (SDS), as the reaction environment. We make GNRs in CTAB system and then use system transform to move GNRs to the System of SDS, in the end we coated silver as shell. In the experiment, we separate in two part to coated silver shell one is GNRs another one is AuDBs each one with high temperature condition and Room temperature condition. We found that if we add metal salt like NaBr or NaCl in high temperature condition, it will have influence to reaction time. Even more will affect the ratio of the shape of gold-silver nanoparticle. Through use the difference meatal salt, and the change of temperature, we could synthesis rectangular, bipyramid and irregular shape, we also have more realize for the shape control and the homogeneity improve.

第一章 緒論	1
1.1	前言	1
1.2	奈米粒子的特性	2
1.3	表面電漿共振	4
1.4	介達電位	5
1.5	金奈米粒子表面保護劑之介紹	6
1.6	奈米微粒之量測科學	7
1.7	研究目的	8
第二章 實驗部分	9
2.1 藥品	9
2.2 儀器	10
1.	紫外光-可見光吸收光譜儀	10
2.	穿透式電子顯微鏡	10
2.3 實驗方法	11
1. 在CTAB條件下製備金奈米棒、啞鈴型	11
2. 系統轉移之方法	14
3.	 在SDS系統下合成金銀核殼之奈米棒	15

第三章 結果與討論	18
3.1金奈米棒(GNRS)、啞鈴型金奈米棒(AuDBs)之製備	18
3.2系統轉移	20
3.3探討添加金屬離子生成金銀核殼型奈米粒子之反應	21
A. 室溫 金奈米棒 包銀	21
B. 高溫 金奈米棒型、啞鈴型包銀	25
3.4 實驗結果與先前文獻作比對和探討	38
第四章 結論	42
第五章 參考資料	44

表目錄
表1.1 Zeta potential於膠體溶液之穩定度	5
表3.1 (SDS) GNRs@Ag 實驗流程圖	21
表3.2 (SDS) GNRs@Ag in HT實驗流程圖	25
表3.3 (SDS) AuDBs@Ag in HT實驗流程圖	31
圖目錄
圖1.1 表面電漿共振示意圖	4
圖1.2 Zeta potential之示意圖	5
圖1.3 金奈米粒子表面吸附不同分子之示意圖	6
圖2.1 製備晶種溶液之示意圖	11
圖2.2 製備GNRs之示意圖	12
圖2.3 製備AuDBs之示意圖	13
圖2.4 系統轉移之示意圖	14
圖2.5 製備GNRs@Ag/AuDBs@Ag之示意圖	16
圖3.1 GNRs 的UV-VIS光譜圖	18
圖3.2 GNRs藉由TEM分析長寬比	19
圖3.3 AuDBs之UV-VIS光譜圖	19
圖3.4 AuDBs之系統轉移UV-VIS光譜圖	20
圖3.5 SDS作為保護劑，GNRs室溫包銀之UV-VIS光譜圖	21
圖3.6 GNRs@Ag採樣40 μL (銀殼成長仍不完全)	22
圖3.7 GNRs@Ag採樣60 μL (銀殼成長較完全)	22
圖3.8 室溫包銀-有無添加EDTA修飾圖	23
圖3.9 UV圖(左) 取樣於包銀70μL之TEM圖	23
圖3.10 UV圖(右) 取樣於包銀60μL之TEM圖	.24
圖3.11 改變AgNO3混合時間之UV圖(右) 	25
圖3.12 GNRs 添加NaCl於高溫包銀之UV-VIS光譜圖	26
圖3.13 GNRs 添加NaCl於高溫包銀之TEM圖	27
圖3.14 GNRs改變AgNO3反應時間之UV圖	28
圖3.15 GNRs 添加NaBr於高溫包銀之UV光譜圖	28
圖3.16 GNRs 添加NaBr於高溫包銀之TEM圖	29
圖3.17 GNRs 添加NaBr、NaCl反應之UV光譜圖比較	30
圖3.18 AuDBs於NaCl下與AgNO3預混合時間改變之UV圖.31
圖3.19 AuDBs添加NaCl於高溫包銀之UV-VIS光譜圖	32
圖3.20 AuDBs 添加NaCl於高溫包銀之TEM圖	33
圖3.21  AuDBs 添加NaBr於高溫包銀之UV-VIS光譜圖	34
圖3.22  AuDBs 添加NaBr於高溫包銀之TEM圖	35
圖3.23 透過Tilt改變角度來觀測 Au@AgDb之形狀	36
圖3.24 AuDBs 添加NaBr、NaCl 於高溫下反應之UV對照圖	37
圖3.25 AuDBs於SDS 和CTAB之不同條件下反應 之UV對照圖	40

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